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1. Project
Evaluation (eNPV) and Licensing Support
a) Scientific/Technical Analysis and Financial
Valuation of R&D Projects
Method:
Risk-adjusted and option-augmented determination of
the expected net
present value (eNVP), based on the discounted cash flow
method
Modules:
·
Product target
profile
·
Decision tree (reflecting development risks,
strategies, timelines and milestones)
·
Market
model
-
Epidemology (populations, incidence/prevalence, future
extrapolations)
-
Market segmentations and patient share (considering
age, gender,
race, state of health, comorbidities, co-medication, 1st/2nd
line therapy,
pre-treatments, ...)
- Treatment modalities
and strategies
- Detailed competitor and
R&D pipeline analysis (and
impact on
market
share)
- Market penetration
and product lifecycle curve
- Product pricing, price trends and distribution costs
--> Regional
and worldwide sales forecasts
·
Intellectual
property incl. freedom-to-operate (FTO) analysis
·
Costs
and financial figures
|
- |
Development
costs |
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- |
Cost of goods |
|
-
a |
Promotional
costs (marketing, sales force, DTC)
and marketing strategies; G&A |
|
- |
Discount
rate, taxes, inflation rates and other financial figures |
·
Financial model
- Discounted cash flows (DCF)
|
-->
a |
Scenario
NPVs, regional and overall eNVP (risk
adjusted, option augmented)
|
· eNVP
projections (future increase of eNPV upon successful completion
of milestones)
· Monte
Carlo simulation (statistical
parameters reflecting uncertainties
of assumptions)
·
Sensitivity analysis (variation
of input variables to test their impact on
key results; alternative scenario modeling)
b)
Drafting of Licensing Deal Terms
·
Generation of a license calculator (modeling
of alternative deal term scenarios)
·
Interactive determination of
optimal deal terms (upfront
and milestone
payments,
royalties and other options)
·
Determination of appropriate
licensee/licensor value splits
2. R&D
Portfolio and Pipeline Analysis
3. Optimization of Preclinical Research
4. R&D
Benchmarking
5.
Multi-Stakeholder Projects
6.
Dedicated Investigations (Competition,
Market Research)
7.
Generation of Documents and Brochures
8.
Part-Time Interims Management
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